Chronic nonbacterial prostatitis

Chronic nonbacterial prostatitis or chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a pelvic pain condition in men occurring from around 20 years of age. Inflammation can be detected in patients, but is not required for the diagnosis. Symptoms like pelvic pain, painful voiding and ejaculation, disturbed sexual functions are common, often resulting in a significant impact on quality of life. Professor J Curtis Nickel, Kingston, Ontario, Canada, reported at the EAU annual meeting 2008 in Milan that the annual cost of a prostatitis patient exceeds that of a patient with type 1 diabetes. He also stated that the quality of life of a man with prostatitis is similar to patients with heart failures or acute Crohn's disease.

Japan and Germany are the only two countries where a drug with the indication CP/CPPS is approved by the health authorities, whereas Cernilton® is one. In other countries, apart from starting with an antibiotic to exclude bacterial cause, there is no medical treatment available for the doctor to prescribe. NSAID and alpha-blockers are frequently prescribed but there is an obvious need for more effective drugs that can alleviate symptoms of CP/CPPS.

With a reported prevalence from 2.2% to 9.7% and a mean prevalence of 8.2%1 CP/CPPS still constitutes a considerable white spot on the urology map and causes a lot of suffering for patients and frustration among doctors not having efficient solutions to alleviate the patient's symptoms.

1. G. Magistro et al. European Urology 69 (2016) 286-297.
2. F. Wagenlehner et al. European Urology 56 (2009) 544-551.