Chronic nonbacterial prostatitis

Chronic nonbacterial prostatitis or chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a pelvic pain condition in men occurring from around 20 years of age. Inflammation can be detected in patients, but is not a prerequisite for the diagnosis. Symptoms like pelvic pain, painful voiding and ejaculation, disturbed sexual functions are common, often resulting in a significant impact on quality of life. Professor J Curtis Nickel, Kingston, Ontario, Canada, reported at the EAU annual meeting 2008 in Milan that the annual cost of a prostatitis patient exceeds that of a patient with type 1 diabetes. He also stated that the quality of life of a man with prostatitis is similar to a patient with a heart attack or acute Crohn's disease.

Japan and Germany are the only two countries where a drug with the indication CP/CPPS is approved by the health authorities, whereas Cernilton® is one. In the other countries, apart from starting with an antibiotic to exclude bacterial cause, there is no medical treatment available for the doctor to prescribe. NSAID and alpha-blockers are frequently tried, successfully in some cases, but there is an obvious need for more effective drugs that can alleviate symptoms of CP/CPPS.

With a reported prevalence from 2.2% to 9.7% and a mean prevalence of 8.2%1 CP/CPPS still constitutes a considerable white spot on the urology map and causes a lot of suffering for patients and frustration among doctors not having efficient solutions to alleviate the patient's symptoms.

1. G. Magistro et al. 2015.
2. Wagenlehner et al. 2009.